Check Yourself — Lesson 5

Answers to Exercise 5

1. In which database (File 452,453,458, 459) will you find the following fields:
   
   
   1. Context Tables    (453)
   2. Chemical image    (452,453,458,459)
   3. A news report from the last month    (458)
   4. List of references    (452,453)
   5. Synthesis scheme    (453)
   
   
2. Write search strategies to retrieve the following information:
   
   
   1. Find the Context Table and related chemical structure images for treatment of colorectal cancer (Therapeutic Class 75025)
      
      S TC=75025
      MAP CX T
      EXS
      T S4/19/1
   
   
   
   2. What format would you use to retrieve a chemical structure image?
      
      IM or 19
   
   
   
   3. What search strategy would you use to find Merck as a patent assignee in File 452?
      
      B 452
      E pa=merck
      S e#s
   
   
   
   4. Find antimigraine drugs developed by Merck. Are there any antimigraine drugs that have been launched in the last couple of years?
      Hint: Do this second part in Daily Essentials.
      
      B 452
      s antimigraine?/tc
      s s1 and lo=merck?
      s s2/pref
      t 3/5/1-2
      b 458, 459
      e st=
      s e8
      s antimigraine?/tc
      s s1 and s2
      s s3 and pd>2000
      t 4/5/1
   
   
   
   5. Which compounds with pain-relieving (analgesic) activity have an indazole group in the molecule? Use therapeutic class (/tc) and chemical name (/cn).
      
      B 452
      s indazole/cn
      s s1 and analges?/tc
      t 2/9/1

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