Basic Index Searching (continued)

?T S1/8/1-5
 
 1/8/1 
DIALOG(R)File  72:(c) 2003 Elsevier Science B.V. All rts. 
reserv. 
 
11950590     EMBASE No: 2003056240 
 Yardenone A and B: New cytotoxic triterpenes from the
  Indian ocean sponge 
Axinella cf. bidderi 
  01 JAN 2003 
DRUG DESCRIPTORS: 
*triterpene derivative--drug analysis--an; *triterpene 
derivative--drug development--dv; *triterpene derivative--
pharmacology--pd; *natural product--drug analysis--an; 
*natural product--drug development--dv; *natural 
product--pharmacology--pd heptane; unclassified drug 
MEDICAL DESCRIPTORS: 
*sponge (Porifera); *cytotoxicity 
extraction; marine environment; chemical composition; 
structure activity relation; stereochemistry; lung non 
small cell cancer; tumor cell line; human; nonhuman; 
controlled study; human cell; article DRUG TERMS 
(UNCONTROLLED): yardenone A--drug analysis--an; 
yardenone A --drug development--dv; yardenone A--
pharmacology--pd; yardenone B--drug analysis--an; 
yardenone B--drug development--dv; yardenone 
B--pharmacology --pd; sodwanone A--drug analysis--an; 
sodwanone A--drug development--dv; sodwanone 
A--pharmacology--pd; Axinella bidderi extract--
drug analysis--an; Axinella bidderi extract--drug 
development--dv; Axinella bidderi extract 
--pharmacology--pd 
MEDICAL TERMS (UNCONTROLLED): Axinella bidderi 
CAS REGISTRY NO.: 142-82-5, 3356-67-0 (heptane) 
 
 
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11909914     EMBASE No: 2003020171 
 Purealidin S and purpuramine J, bromotyrosine 
alkaloids from the Fijian marine sponge Druinella sp 
  01 DEC 2002 
DRUG DESCRIPTORS: 
*alkaloid derivative--drug comparison--cm; *alkaloid 
derivative--drug development--dv; *alkaloid derivative--
pharmacology--pd unclassified drug 
MEDICAL DESCRIPTORS: 
sponge (Porifera); drug isolation; drug cytotoxicity; 
bioassay; proton nuclear magnetic resonance; carbon nuclear 
magnetic resonance; antineoplastic activity; cancer cell 
culture; drug synthesis; drug potency; human; controlled 
study; human cell; article DRUG TERMS (UNCONTROLLED): 
purealidin S--drug comparison--cm; purealidin S--drug 
development--dv; purealidin S--pharmacology--pd; 
purpuramine J--drug comparison--cm; purpuramine J--drug 
development--dv; purpuramine J--pharmacology--pd 
 
 
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DIALOG(R)File  72:(c) 2003 Elsevier Science B.V. All rts. 
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11866440     EMBASE No: 2002430931 
 Five new discodermolide analogues' from the 
marine sponge Discodermia species
  2002 
DRUG DESCRIPTORS: 
*discodermolide--drug analysis--an; *discodermolide--drug 
development--dv; *discodermolide--drug toxicity--to 
unclassified drug 
MEDICAL DESCRIPTORS: 
sponge (Porifera); Caribbean Islands; drug isolation; 
structure activity relation; drug activity; cytotoxicity; 
drug potency; cancer cell culture; human; nonhuman; 
controlled study; human cell; animal cell; article 
DRUG TERMS (UNCONTROLLED): 2 discodermolide--drug 
analysis--an; 2 discodermolide--drug development--dv; 2 
discodermolide--drug toxicity--to; 2 methyldiscodermolide
--drug analysis--an; 2 methyldiscodermolide--drug 
development--dv; 2 methyldiscodermolide--drug toxicity--
to; 5 hydroxymethyldiscodermolate--drug analysis--an; 5 
hydroxymethyldiscodermolate--drug development--dv; 5 
hydroxymethyldiscodermolate--drug toxicity--to; 19 
aminocarbonyldiscodermolide--drug analysis--an; 19 
aminocarbonyldiscodermolide--drug development--dv; 19 
aminocarbonyldiscodermolide--drug toxicity--to; 9(13) 
cyclodiscodermolide--drug analysis--an; 9(13) 
cyclodiscodermolide--drug development--dv; 9(13) 
cyclodiscodermolide--drug toxicity--to 
MEDICAL TERMS (UNCONTROLLED): Discodermia 
CAS REGISTRY NO.: 127943-53-7, 154335-30-5, 194232-29-6 
(discodermolide) 
 
 
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11820967     EMBASE No: 2002392657 
 Axinellin C, a proline-rich cyclic octapeptide 
isolated from the Fijian marine sponge Stylotella 
aurantium 
  23 SEP 2002 
DRUG DESCRIPTORS: 
*octapeptide--drug analysis--an; *octapeptide--drug 
development--dv; * octapeptide--pharmacology--pd 
cyclopeptide; unclassified drug 
MEDICAL DESCRIPTORS: 
*drug isolation nuclear magnetic resonance; tandem mass 
spectrometry; conformational transition; calculation; 
crystal structure; amino acid sequence; structure 
activity relation; cancer cell culture; drug cytotoxicity; 
human; controlled study; human cell; article; priority 
journal DRUG TERMS (UNCONTROLLED): axinellin c--drug 
analysis--an; axinellin c--drug development--dv; axinellin 
c--pharmacology--pd; phakelistatin 8 
 
 
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11814007     EMBASE No: 2002386141 
 Pachastrissamine, a cytotoxic 
anhydrophytosphingosine from a marine sponge, 
Pachastrissa sp. 
  01 OCT 2002 
BRAND NAME/MANUFACTURER NAME: krn 7000 
DRUG DESCRIPTORS: 
*cytotoxic agent--drug analysis--an; *cytotoxic agent--
drug development--dv; *cytotoxic agent--pharmacology--
pd 1 o (alpha galactopyranosyl) 2 hexacosanoylamino 
1,3,4 octadecanetriol--drug analysis--an; 1 o (alpha 
galactopyranosyl) 2 hexacosanoylamino 1,3,4 
octadecanetriol--drug development--dv; 1 o (alpha 
galactopyranosyl) 2 hexacosanoylamino 1,3,4 
octadecanetriol--pharmacology--pd; unclassified 
drug 
MEDICAL DESCRIPTORS: 
*drug isolation; *cytotoxicity; *sponge (Porifera) 
drug activity; antineoplastic activity; drug structure; 
nuclear magnetic resonance spectroscopy; structure 
analysis; cancer cell culture; human; nonhuman; mouse; 
controlled study; human cell; animal cell; article 
DRUG TERMS (UNCONTROLLED): pachastrissamine--drug 
analysis--an; pachastrissamine--drug development--dv; 
pachastrissamine--pharmacology--pd; 
anhydrophytosphingosine--drug analysis--an; 
anhydrophytosphingosine--drug development--dv; 
anhydrophytosphingosine--pharmacology--pd 
MEDICAL TERMS (UNCONTROLLED): Pachastrissa 
CAS REGISTRY NO.: 158021-47-7 (1 o (alpha 
    galactopyranosyl) 2 hexacosanoylamino 1,3,4 
    octadecanetriol)