Displaying Records (continued)
A good format I can use to preview the content of the record is the KWIC or Keyword in Context format (Format K). This format allows me to see a window of 30 words around my search terms. It gives me more information about the topic so I can tell whether the record is pertinent to my research needs.
To display more of the records, I enter the TYPE command, identifying the records I want to view in a more detailed format. Looking at records 2 and 5 should give us an idea of what the scientific literature is saying about the use of coral for treating bone.
t s4/8,k/1-5
We can see by looking at the excerpts from these records that this treatment is really being tested. I think I'll keep these in case Brian wants more records to choose from.
Go to next page when you have finished browsing the records below.
?4/8,K/1
DIALOG(R)File 155:(c) format only 1999 Dialog Corporation.
All rts. reserv.
09922651 99164908
The use of coralline hydroxyapatite with
bone marrow, autogenous bone graft, or osteoinductive
bone protein extract for posterolateral lumbar
spine fusion.
Feb 15 1999
Tags: Animal; Comparative Study; Female; Support,
Non-U.S. Gov't
Descriptors: Biocompatible Materials; * Bone
Marrow Transplantation-- Methods--MT; *Bone
Transplantation--Methods--MT; *Ceramics; *Durapatite;
*Lumbar Vertebrae-- Surgery --SU;
*Spinal Fusion--Methods--MT; Biomechanics; Bone
Substitutes ; Bone Transplantation--Pathology--PA
; Calcium Hydroxide; Disease Models, Animal;
Follow-Up Studies; Ilium--Transplantation--TR;
Lumbar Vertebrae--Pathology--PA; Lumbar
Vertebrae--Radiography--RA; Postoperative
Complications; Rabbits; Treatment Outcome; Zinc
CAS Registry No.: 0 (coralline sulfate);
0 (osteoinductal); 0 (Biocompatible Materials);
0 (Bone Substitutes); 0
(Ceramics); 1305-62-0 (Calcium Hydroxide);
1306-06-5 (Durapatite); 7440-66-6 (Zinc)
The use of coralline hydroxyapatite with
bone marrow, autogenous bone graft, or osteoinductive
bone protein extract for posterolateral lumbar
spine fusion.
STUDY DESIGN: A posterolateral lumbar
arthrodesis animal model using coralline
hydroxyapatite as a bone graft substitute .
OBJECTIVE: To determine the effectiveness of
coralline hydroxyapatite as a bone graft substitute
for lumbar spine fusion when used with bone marrow,
autogenous bone graft , or an osteoinductive bone
protein extract.
SUMMARY OF BACKGROUND DATA: Coralline hydroxyapatite
is commonly used as a bone graft substitute in
metaphysial defects but its use in a more challenging
healing environment such as the posterolateral
spine remains controversial. There are no published
animal studies in which the use of coralline
hydroxyapatite has been evaluated in a posterolateral
lumbar arthrodesis model.
METHODS: Single-level posterolateral lumbar...
... New Zealand White rabbits. Rabbits were assigned
to one of three groups based on the graft
material they received: 3.0 mL coralline
hydroxyapatite 1.5 mL plus bone marrow;
1.5 mL coralline hydroxyapatite plus 1.5 mL
autogenous iliac crest bone ; and, 3.0 mL coralline
hydroxyapatite plus 500 micrograms
bovine-derived osteoinductive bone protein extract
on each side. Rabbits were killed after 2, 5, or
10 weeks, and...
... were assessed by manual palpation at 5 weeks for
comparisons among the three groups of graft materials.
The coralline hydroxyapatite used with bone marrow
produced no solid fusions (0/14). When combined with an
equal amount of autogenous iliac crest bone ,
coralline hydroxyapatite resulted in solid fusion
in 50% (7/14) of the rabbits (P < 0.05).
When combined with the osteoinductive growth
factor extract, the coralline hydroxyapatite resulted
in solid fusion in 100% (11/11) of the rabbits
(P < 0.05...
... testing to failure when normalized to the
adjacent unfused level.
CONCLUSION: These data indicate that coralline
hydroxyapatite with bone marrow was not an
acceptable bone graft substitute for
posterolateral spine fusion. When combined
with autogenous iliac crest bone graft -
coralline hydroxyapatite served as a graft
extender yielding results comparable to those
obtained with autograft alone.
Coralline hydroxyapatite served as an excellent
carrier for the bovine osteoinductive bone
protein extract yielding superior results to those
obtained with autograft or bone marrow.
Descriptors: Biocompatible Materials; * Bone
Marrow Transplantation-- Methods--MT; *Bone
Transplantation--Methods--MT; *Ceramics; *Durapatite;
*Lumbar Vertebrae-- Surgery --SU;
*Spinal Fusion--Methods--MT; Biomechanics; Bone
Substitutes ; Bone Transplantation--Pathology--PA;
Calcium Hydroxide; Disease Models, Animal;
Follow-Up Studies; Ilium--Transplantation--TR;
Lumbar...
Chemical Name: coralline
sulfate; (osteoinductal; (Biocompatible Materials;
( Bone Substitutes ; (Ceramics;
(Calcium Hydroxide;(Durapatite; (Zinc
4/8,K/2
DIALOG(R)File 155:(c) format only 1999 Dialog Corporation.
All rts. reserv.
09919454 99229015
Evaluation of combinations of titanium, zirconia,
and alumina implants with 2 bone fillers in the dog.
Mar-Apr 1999
Tags: Animal; Comparative Study
Descriptors: Bone Substitutes ; *Dental
Implantation , Endosseous--Methods--MT; *Dental
Implants ; *Osseointegration; Aluminum Oxide;
Calcium Phosphates; Cnidaria; Dogs; Durapatite;
Surface Properties; Titanium; Tooth Socket; Zirconium
CAS Registry No.: 0 (Bone Substitutes);
0 (Calcium Phosphates); 0 (Dental Implants);
1306-06-5 (Durapatite); 1314-23-4
(zirconium oxide); 1344-28-1 (Aluminum Oxide);
7440-32-6 (Titanium); 7440-67-7(Zirconium)
Evaluation of combinations of titanium, zirconia,
and alumina implants with 2 bone fillers in the dog.
The quality of the tissue-implant interface was
evaluated using light and scanning electron microscopy
with morphometric analysis. Nine dogs were implanted
with 3 types of dental implants (titanium,
zirconia, or alumina). A total of 24
dental implants was placed in mandibular bone
previously filled with coral carbonate
calcium (corail) or hydroxyapatite. The study
results in breaking the concept of
osseointegration into 2 phases: "osseocoaptation,"
which concerns only the interface (physical contact
between the implants and the bone without
interpenetration process), and "osseocoalescence,"
which relies on an interpenetration of the
bioactive material, which almost entirely disappears,
being substituted by newly formed bone . There
was no significant statistical difference between
the 3 types of implants . Both fillings showed good
ossecoalescence properties. However, hydroxyapatite
led to fibrous encystment, preventing
osseocoaptation of implants . In contrast with
calcium carbonate filling.
Descriptors: Bone Substitutes ; *Dental Implantation ,
Endosseous--Methods--MT;
*Dental Implants ; *Osseointegration
Chemical Name: Bone Substitutes ; (Calcium
Phosphates; (Dental Implants ; (Durapatite;
(zirconium oxide; (Aluminum Oxide; (Titanium; (Zirconium
4/8,K/3
DIALOG(R)File 155:(c) format only 1999 Dialog Corporation.
All rts. reserv.
09867256 99135153
[Biomaterials in an osteo-articular environment.
Report of 129 anatomoclinical cases]
Biomateriaux en milieu osteo-articulaire. A propos
de 129 observations anatomocliniques.
Sep 1998
Tags: Human
Descriptors: *Biocompatible Materials; *Ceramics;
*Joint Prosthesis; *Polymers; Bone Conduction;
Ploidies
CAS Registry No.: 0 (Biocompatible Materials);
0 (Ceramics); 0 (Polymers)
... synthetic or metallic (or the both). They are
employed as prosthesis (biostability property) or
as bone graft (bioresorbability property).
To understand the interactions between cells and such
materials, we studied with human bone cellular
cultures the cytologycal, immunohistochemical,
cytogenetical and ultrastructural aspects of
biomaterials in cell cultures. This paper concerns
bioceramics like Pyrost, coral , biosorb, oxbone and
polymers like polyethylene and silicones. The aim
of this work is to...
... the efficiency of some biomaterials. We
found that porosity is primordial to promote
biodegradation of bone substitutes . In fact, the
biomaterials is integrated and lead to
an osteoconduction, an osteoformation and finally
an osteoinduction. Our observations show the implant
resorption and ossification occurring in the
matrix which penetrate it.
; Bone Conduction; Ploidies
4/8,K/4
DIALOG(R)File 155:(c) format only 1999 Dialog Corporation.
All rts. reserv.
09842778 99084700
A 5-year follow-up of 16 patients treated with
coralline calcium carbonate (BIOCORAL) bone replacement
grafts in infrabony defects.
Dec 1998
Tags: Animal; Female; Human; Male; Support,
Non-U.S. Gov't
Descriptors: Absorbable Implants ; *Alveolar Bone
Loss--Surgery --SU; * Bone Substitutes --Therapeutic
Use--TU; * Bone Transplantation--
Methods--MT; *Calcium Carbonate--Therapeutic
Use--TU; Adult; Aged; Analysis of Variance;
Bone Regeneration; Cnidaria; Follow-Up Studies;
Middle Age; Periodontal Pocket--Surgery --SU;
Statistics, Nonparametric; Treatment Outcome
CAS Registry No.: 0 (Bone Substitutes); 471-34-1
(Calcium Carbonate)
A 5-year follow-up of 16 patients treated with
coralline calcium carbonate (BIOCORAL) bone replacement
grafts in infrabony defects. A resorbable coralline
calcium carbonate graft material (BIOCORAL)(CalCarb)
was evaluated as a bone replacement graft
in human periodontal osseous defects. Following
initial preparation and re-evaluation, flap surgery
was carried out. Bone defects were curetted and root
surfaces subjected to mechanical debridement and
conditioning with tetracycline paste. The bone defects
were grafted with CalCarb, and the host flaps replaced
or slightly coronally positioned. Weekly, then
monthly deplaquing was performed until surgical
reentry at 6...
... changes included improvement in mean vertical
clinical probing attachment level from 5.7 mm at
surgery to 4.2 mm at re-entry to 4.0 mm at 5 years,
decrease in mean probing pocket depth from 6.1 mm at
surgery to 3.0 mm at re-entry to 3.3 mm at 5 years,
and mean gingival recession from +0.4 mm at surgery
to 1.0 mm at re-entry to 0.7 mm at 5 years (all at
least p<0.05 from surgery to re-entry and surgery
to 5 years, N.S. from reentry to 5 years via ANOVA).
These favorable long...
Descriptors: Absorbable Implants ; *Alveolar Bone
Loss--Surgery --SU; * Bone Substitutes --Therapeutic
Use--TU; * Bone Transplantation--Methods--MT;
*Calcium Carbonate--Therapeutic Use--TU; Adult;
Aged; Analysis of Variance; Bone Regeneration;
Cnidaria; Follow-Up Studies; Middle Age; Periodontal
Pocket--Surgery --SU; Statistics, Nonparametric;
Treatment Outcome
Chemical Name: Bone Substitutes ; (Calcium Carbonate
4/8,K/5
DIALOG(R)File 155:(c) format only 1999 Dialog Corporation.
All rts. reserv.
09824317 99116171
Current understanding of osteoconduction in bone
regeneration.
Oct 1998
Tags: Human
Descriptors: Bone and Bones --Physiology--PH;
*Bone Regeneration-- Physiology--PH;
Biocompatible Materials--Chemistry--CH; Biodegradation;
Bone and Bones --Anatomy and Histology--AH;
Bone and Bones--Chemistry--CH; Bone Substitutes --
Chemistry--CH; Calcium-- Chemistry--CH;
Ceramics--Chemistry--CH; Collagen--Chemistry--CH;
Collagen--Physiology--PH; Hydroxyapatites--Chemistry--CH;
Lactic Acid--Chemistry --CH; Metals--Chemistry--CH;
Minerals; Polyglycolic Acid--Chemistry--CH;
Polymers--Chemistry-- CH; Porosity
CAS Registry No.: 0 (polylactic acid-polyglycolic
acid copolymer);
0 (Biocompatible Materials);
0 (Bone Substitutes); 0 (Ceramics);
0 (Hydroxyapatites); 0 (Metals);
0 (Minerals); 0 (Polymers); 26009-03-0
(Polyglycolic Acid); 50-21-5
(Lactic Acid); 7440-70-2
(Calcium); 9007-34-5 (Collagen)
Current understanding of osteoconduction in bone
regeneration.
Bone tissue is osteoconductive. In particular,
cancellous bone with its porous and highly
interconnected trabecular architecture allows
easy ingrowth of surrounding tissues. When...
... living tissue for the host bed migrates into
the cancellous structure, which results in new bone
formation and incorporation of that structure.
This is the process of osteoconduction. The
mineral and collagenous components of bone are
osteoconductive. Osteoconduction also is observed
in fabricated materials that have porosity
similar to that of bone structure. Corallin
ceramics, hydroxyapatite beads, and combinations
of hydroxyapatite and collagen all have
osteoconductive properties, and porous metals
and biodegradable polymers. Osteoconduction appears
to be optimized in devices that mimic not only bone
structure, but also bone chemistry.
The incorporation of calcium salts and collagen by
osteoconductive matrices leads to more complete
ingrowth with new bone formation.
Descriptors: Bone and Bones --Physiology--PH;
*Bone Regeneration-- Physiology--PH;
Biocompatible Materials--Chemistry--CH; Biodegradation;
Bone and Bones --Anatomy and
Histology--AH; Bone and Bones--Chemistry--CH;
Bone Substitutes --Chemistry--CH; Calcium--
Chemistry--CH; Ceramics--Chemistry--CH;
Collagen--Chemistry--CH; Collagen--Physiology--PH;
Hydroxyapatites...
Chemical Name: polylactic acid-polyglycolic
acid copolymer; (Biocompatible Materials;
(Bone Substitutes;(Ceramics; (Hydroxyapatites;
(Metals; (Minerals; (Polymers; (Polyglycolic Acid;
(Lactic Acid; (Calcium; (Collagen
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