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DIALOG(R)File 155:MEDLINE(R)
(c) format only 1999 Dialog Corporation. All rts. reserv.


09842778   99084700
  A  5-year  follow-up  of  16  patients  treated with  
coralline calcium carbonate (BIOCORAL)  bone  replacement  
grafts in infrabony defects.
  Yukna RA; Yukna CN
  Department   of   Periodontics,  Louisiana  State  
University  School  of Dentistry, New Orleans 70119, USA.
  J   Clin   Periodontol (DENMARK)   Dec   1998,  25  (12) 
  p1036-40,  
ISSN 0303-6979   Journal Code: HT7
  Languages: ENGLISH
  Document type: JOURNAL ARTICLE
  JOURNAL ANNOUNCEMENT: 9904
  Subfile:   INDEX MEDICUS; DENTAL
  A  resorbable  coralline   calcium carbonate graft  
material (BIOCORAL) (CalCarb)  was  evaluated  as  
a  bone     replacement  graft  in human periodontal   
osseous   defects.   Following   initial preparation   
and re-evaluation, flap surgery  was carried out. Bone  
defects were curetted and root surfaces subjected to 
mechanical debridement and conditioning with 
tetracycline paste. The bone  defects were grafted 
with CalCarb, and the host  flaps  replaced   or  
slightly  coronally positioned.  Weekly, then monthly  
deplaquing  was  performed  until surgical reentry 
at 6-12 months. Patients  were  then  followed  on
approximate 3 month recalls for > or =5 years.  
Significant  clinical changes included improvement 
in mean vertical clinical  probing  attachment  
level  from 5.7 mm at surgery  to 4.2 mm at re-entry  
to  4.0 mm at 5 years, decrease in mean probing pocket 
depth from 6.1  mm  at  surgery  to 3.0 mm at re-entry 
to 3.3 mm at 5 years, and mean gingival  recession  
from +0.4 mm at surgery  to 1.0 mm atre-entry to 0.7 mm  
at 5 years (all at least p<0.05 from surgery  
to re-entry and surgery to  5  years,  N.S.  from  
reentry  to  5 years via ANOVA). These favorable long-term  
results  with CalCarb suggest that CalCarb may have a 
beneficial effect in the long-term clinical management 
of infrabony defects.
  Tags: Animal; Female; Human; Male; Support, 
Non-U.S. Gov't
  Descriptors: Absorbable Implants ; *Alveolar Bone  
Loss--Surgery --SU;* Bone     Substitutes  --Therapeutic  
Use--TU;  * Bone   Transplantation--Methods--MT;   
*Calcium   Carbonate--Therapeutic  Use--TU;  Adult;  
Aged; Analysis  of  Variance;  Bone   Regeneration; 
Cnidaria; Follow-Up Studies; Middle  Age;  Periodontal 
Pocket--Surgery --SU; Statistics, Nonparametric; 
Treatment Outcome
  CAS Registry No.: 0   (Bone Substitutes); 
471-34-1(Calcium Carbonate)

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