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Dialog "How Do I...?" - Pharmaceuticals & Health Devices

Locate Information on New Drugs Coming on the Market for a Particular Indication?

TOPIC: In this example, using International Pharmaceutical Abstracts (File 74), you want to find information on new drugs that might come on the market for rheumatoid arthritis. IPA provides information on all phases of the development and use of drugs worldwide.

 

COMMAND SUMMARY

BEGIN 74
SELECT RHEUMATOID()ARTHRITIS
SELECT S1 AND NEW()DRUG?
SELECT S2/2005:2006
TYPE S3/6/1-4
TYPE S3/9/1


HOW TO...



1. BEGIN 74, a database containing information about phases of drug development worldwide.

2. SELECT the disease name.

3. Narrow the search to “new drugs” and to the current year(s).



?b 74

File  74:Int.Pharm.Abs 1970-2006/Jul B1
       (c) 2006 The Thomson Corporation
 
      Set  Items  Description
      ---  -----  -----------
?SELECT RHEUMATOID()ARTHRITIS
            2638  RHEUMATOID
            3891  ARTHRITIS
      S1    2540  RHEUMATOID()ARTHRITIS

?SELECT S1 AND NEW()DRUG?
            2540  S1
           41197  NEW
          294114  DRUG?
            4103  NEW(W)DRUG?
      S2      54  S1 AND NEW()DRUG?

?S S2/2005:2006
              54  S2
           26844  PY=2005 : PY=2006
      S3       6  S2/2005:2006



4. TYPE
a few records for relevance using Format 6.


?T S3/6/1-4
 
  3/6/1  
00425705  43-08685
ABATACEPT (<IT>ORENCIA</IT>) FOR RHEUMATOID   ARTHRITIS  
Publication Year: 2006   
 
  3/6/2  
00421444  43-04424
USING EPIDEMIOLOGY AND ARCHAEOLOGY TO UNEARTH NEW DRUG TARGETS FOR RHEUMATOID ARTHRITIS THERAPY
Publication Year: 2006  
  
  3/6/3  
00404003  42-09469
EFFICACY, TOLERABILITY AND COST EFFECTIVENESS OF DISEASE-MODIFYING
ANTIRHEUMATIC DRUGS AND BIOLOGIC AGENTS IN RHEUMATOID ARTHRITIS  
Publication Year: 2005  
 
  3/6/4  
00402923  42-08388
ADOPTION OF CELECOXIB AND ROFECOXIB: A NATIONWIDE DATABASE STUDY
Publication Year: 2005  


5. TYPE
a desired record(s) in Format 9 to see the complete record.


?T S3/9/1
 
  3/9/1  
DIALOG(R)File  74:Int.Pharm.Abs
(c) 2006 The Thomson Corporation. All rts. reserv.
 
00425705  43-08685
ABATACEPT (<IT>ORENCIA</IT>) FOR RHEUMATOID   ARTHRITIS  
Anonymous Medical Letter on Drugs and Therapeutics (USA), V48, (1229), p17-18, 2006
CODEN: MELEAP  ISSN: 0025-732X  LANGUAGE: English  RECORD TYPE: Abstract
     An overview of a novel drug, abatacept (Orencia) approved for the treatment of rheumatoid arthritis is presented, including mechanism of action, pharmacokinetics, clinical efficacy, and adverse effects. (9 references)
 
CAS REGISTRY NUMBERS: 332348-12-6 (Abatacept)
CHEMICAL/BRAND NAMES: Orencia
DESCRIPTORS: Mechanism of action -- abatacept; Pharmacodynamics --
  abatacept; Pharmacokinetics -- abatacept; Blood levels -- abatacept; Excretion -- abatacept; Toxicity -- abatacept; Dosage -- abatacept; Arthritis -- abatacept; Half life -- abatacept; Costs -- abatacept; Drugs -- new  ; Drugs -- approvals; Food and Drug Administration (U.S.) -- approvals
SECTION HEADINGS: Pharmacology (11); Toxicity (04); Drug evaluations (06); Drug metabolism & body distribution (15)

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Stock #: 54325; Last modified: 14 Sep 2011



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