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Find Peer-reviewed Studies in Biomedical Literature for a Specific Drug and Indication?
TOPIC: In this example, using two biomedical databases MEDLINE® (File 154) and EMBASE® (File 72), you want to find recent human research studies in English for the drug Baclofen, a drug used for spasticity and pain. MEDLINE® is a major source of biomedical literature. EMBASE® also contains biomedical information with a focus on drug literature. Both databases have their own thesaurus to help in locating search terms.
COMMAND SUMMARY
BEGIN 154,72
SELECT BACLOFEN/TI,DE
SELECT S1 AND SPASTICITY/TI,DE
SELECT S2/HUMAN,ENG,2005
SELECT S3 NOT CEREBRAL()PALSY
RD
TYPE S5/6/1-2 FROM EACH
Using Record Links, click Links > Display > Full Record
HOW TO...
1. BEGIN 154 and 72, databases containing biomedical and drug literature.
2. SELECT the drug name and disease limited to the title (/TI) and descriptors (/DE).
3. Limit the set to human subjects (/human) and English language records (/eng) from 2005 (/2005).
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4. Eliminate records related to “cerebral palsy.”
5. Remove duplicate records (RD) when searching more than one database.
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6. TYPE S5 in Format 6 and use the FROM EACH command to see the first two records from each database.
7. Click Links > Display > Full Record to see the entire record.
You can click Links > Toxicology to retrieve toxicology literature for the CAS Registry Number.
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The full record displays.
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RELATED HOW DO I...? SOLUTIONS
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