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Find Articles in EMBASE Using a GenBank Accession Number?
TOPIC: EMBASE® (File 72,73), the online equivalent of Excerpta Medica Abstract Journals, is the most current biomedical database available today. Articles appear online, on average, within two weeks of receipt of the original journal. Each record is indexed by medical research specialists who assign terms and codes in accordance with EMTREE, a highly developed classification schedule and controlled vocabulary. With more than 580,000 abstracts and citations added annually, EMBASE provides Digital Object Identifiers (DOI), the ability to link from specific records to the fulltext articles with graphs, charts and pictures. Clicking a DOI may take you directly to the fulltext of the document or to a professional society website that restricts display to members only or to the publisher’s website, where you may purchase the complete article. In addition, some records present URLs that link directly to the fulltext. For searchers with Dialog eLinks enabled, EMBASE displays links to their electronic journal subscriptions right from their search results.
In EMBASE, biotechnology-related articles contain molecular sequence numbers. These sequence numbers, residing in the Molecular Sequence Number field (SQ=), identify accession numbers found in various databanks and repositories. Searchers looking for information on novel therapeutics and related topics use this field with ease. EMBASE molecular sequence number indexing includes:
Nucleotide sequence numbers:
• GenBank
• EMBL (European Molecular Biology Laboratory)
• DDBJ (DNA Data Bank of Japan)
Protein sequence numbers:
• SWISSPROT
• PIR (Protein Identification Resource)
This example involves a query to find articles that contain the GenBank accession number U88880. This is all the information you have. You think the patron is looking for an article about the treatment of asthma epidemiology.
COMMAND SUMMARY
BEGIN 72
EXPAND SQ=U88880
SELECT E3
SELECT S1 AND ASTHMA?
TYPE S1/9/9
HOW TO...
1. BEGIN File 72 to search EMBASE from 1993 to the present.
Note that File 73 contains records from 1974 to the present.
2. EXPAND the GenBank sequence number using the prefix SQ=.
3. SELECT the appropriate “E” Reference number. |
?b 72
File 72:EMBASE 1993-2008/Jul 08
(c) 2008 Elsevier B.V.
Set Items Description
--- ----- -----------
?expand sq=u88880
Ref Items Index-term
E1 32 SQ=U88878
E2 24 SQ=U88879
E3 43 *SQ=U88880
E4 10 SQ=U88881
E5 1 SQ=U88882
E6 1 SQ=U88885
E7 1 SQ=U88887
E8 1 SQ=U88888
E9 2 SQ=U88889
E10 17 SQ=U88891
E11 4 SQ=U88893
E12 2 SQ=U88894
E13 1 SQ=U88896
(…)
Enter P or PAGE for more
?select e3
S1 43 SQ='U88880' |
4. Narrow results by combining Search Set 1 (S1) with another concept.
|
?s s1 and asthma?
43 S1
71487 ASTHMA?
S2 1 S1 AND ASTHMA?
|
5. TYPE selected record(s) in Format 9. This Full format contains the bibliographic citation, abstract, indexing, descriptors, author contact details and special links.
Notice the icon for Swets on this eLink enabled account.
This record contains both an Item Identifier (DOI) and a URL that launches the fulltext. |
?t s1/9/9
Dialog eLink: Swets
1/9/9
DIALOG(R)File 72: EMBASE
(c) 2008 Elsevier B.V. All rights reserved.
0081105865 EMBASE No: 2006167614
A brief targeted review of susceptibility factors, environmental exposures, asthma incidence, and recommendations for future asthma incidence research
Yeatts K.; Sly P.; Shore S.; Weiss S.; Martinez F.; Geller A.; Bromberg P.; Enright P.; Koren H.; Weissman D.; Selgrade M.J.
Center for Environmental Medicine, Asthma, and Lung Biology, School of Medicine, University of North Carolina-Chapel Hill, 104 Mason Farm Rd., Chapel Hill, NC 27559-7310, United States
Author email: Karin; Yeatts@unc.edu
Corresp. Author/Affil: Yeatts K.: Center for Environmental Medicine, Asthma, and Lung Biology, School of Public Health, University of North Carolina-Chapel Hill, 104 Mason Farm Rd., Chapel Hill, NC 27599-7310, United States
Corresp. Author Email: Karin; Yeatts@unc.edu
Environmental Health Perspectives ( Environ. Health Perspect. ) ( United States ) April 1, 2006 , 114/4 (634-640)
ISSN: 0091-6765 eISSN: 1552-9924
Item Identifier (DOI): 10.1289/ehp.8381
URL: http://www.ehponline.org/members/2006/8381/8381.pdf
Document Type: Journal ; Review Record Type: Abstract
Language: English Summary language: English
Number of References: 118
Relative to research on effects of environmental exposures on exacerbation of existing asthma, little research on incident asthma and environmental exposures has been conducted. However, this research is needed to better devise strategies for the prevention of asthma. The U.S. Environmental Protection Agency (EPA) and National Institute of Environmental Health Sciences held a conference in October 2004 to collaboratively discuss a future research agenda in this area. The first three articles in this mini-monograph summarize the discussion on potential putative environmental exposure; they include an overview of asthma and conclusions of the workshop participants with respect to public health actions that could currently be applied to the problem and research needs to better understand and control the induction and incidence of asthma, the potential role of indoor/outdoor air pollutants in the induction of asthma), and biologics in the induction of asthma. Susceptibility is a key concept in the U.S. EPA "Asthma Research Strategy" document and is associated with the U.S. EPA framework of protecting vulnerable populations from potentially harmful environmental exposures. Genetics, age, and lifestyle (obesity, diet) are major susceptibility factors in the induction of asthma and can interact with environmental exposures either synergistically or antagonistically. Therefore, in this fourth and last article we consider a number of "susceptibility factors" that potentially influence the asthmatic response to environmental exposures and propose a framework for developing research hypotheses regarding the effects of environmental exposures on asthma incidence and induction.
Molecular Sequence Number: GENBANK U88878; GENBANK U88880; GENBANK X06882
Drug Descriptors:
CD14 antigen--endogenous compound--ec; cigarette smoke--drug toxicity--to; fish oil; toll like receptor 2--endogenous compound--ec; toll like receptor 4--endogenous compound--ec
Medical Descriptors:
* asthma--epidemiology--ep; *asthma--etiology--et; *asthma--prevention--pc; * asthma--therapy--th; *disease predisposition; *environmental exposure age; atopy--etiology--et; cigarette smoking; diet; dietary intake; disease course; environmental sanitation; genetic polymorphism; genetic susceptibility; genotype environment interaction; government regulation; human; incidence; lifestyle; maternal nutrition; medical research; nucleotide sequence; obesity--etiology--et; occupational exposure; prenatal exposure; priority journal; prophylaxis; protective clothing; public health ; review; United States
CAS Registry Number: 8016-13-5 (fish oil); 203811-81-8 (toll like receptor 2); 203811-83-0 (toll like receptor 4)
SECTION HEADINGS:
Chest Diseases, Thoracic Surgery and Tuberculosis
Public Health, Social Medicine and Epidemiology
Occupational Health and Industrial Medicine
Environmental Health and Pollution Control
General Pathology and Pathological Anatomy
Toxicology |
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