Dear Colleague

The American Chemical Society Spring 2006 meeting is scheduled for March 26-30 in Atlanta, Georgia. Dialog will be exhibiting at the meeting as part of the Thomson Scientific booth (#402 and #404). Drop by and find out more about Dialog, DataStar, Derwent, Thomson Pharma and Reference Manager.

I also would like to invite you to the session I am presenting on "Chemical Structure Searching in Multiple Drug Pipeline Databases using DialogLink 5" on Tuesday, March 28.

The session focuses on using the Chemical Structure Search module in DialogLink 5 to search five drugs-in-development databases on Dialog to check to see if a target molecule is already in development or if it's near clinical trials. Searching simultaneously across multiple databases increases the odds that you won’t miss something important. It is now easier to identify a potentially competitive compound earlier in the development process.

Check your program for the exact time of the session in the Presentation Theatre.

Bob Stewart
Chemical Market

RAJ: Healthcare Information Available on Dialog

A new file, Regulatory Affairs Journals, or RAJ (File 183), has been launched on Dialog. This file contains two publications from PJB, the provider of Scrip and Pharmaprojects: Regulatory Affairs Journal — Pharma and Regulatory Affairs Journal — Devices. RAJ — Pharma has established a worldwide reputation as the primary source of international regulatory intelligence, news and opinion for the pharmaceutical, biotech and veterinary industries, as well as government health authorities and the regulatory agencies. RAJ — Devices fulfils a similar role for the medical device and in vitro diagnostics sectors worldwide.

File 183 is updated daily while the printed version of RAJ — Pharma is updated monthly and RAJ — Devices is updated bimonthly. Refer to the Bluesheet of File 183 for further information and search tips. RAJ is also available on DataStar (PHRJ).

IPCR/8 Update

As previously announced, the new International Patent Classification Reform – Version 8 (IPCR/8) took effect January 1, 2006. At this point, most of the major patent files are updating regularly with the new coding.

Chemistry users should take particular note that CA SEARCH (patent subset) (Files 399,314) are now online with new coding. CA SEARCH®: Chemical Abstracts® (CHZZ, CHEM) on DataStar are also affected.

New Feature: Attribute Searching
Each IPCR/8 classification code is also accompanied by a series of "Attributes" or properties of the classification. These Attributes are very important to the patent searcher because under IPCR/8 not all assigned classification codes are of equal significance.

Attributes can be searched using the IA= field which is now present in European Patents Fulltext (File 348), U.S. Patents Fulltext (File 654), WIPO/PCT Patents Fulltext (File 349), and CA Search (Files 399, 314). Consult the IPCR/8 Web page for a list of valid Attribute codes, search examples and more details.

In an effort to keep you up-to-date on the IPCR/8 classifications and how Dialog is implementing the changes, a dedicated Web page has been created. A full list of Dialog databases affected by the changes also is available on this Web page. This page will be updated regularly to provide relevant information regarding the current status of changes to those databases.

Alerts with Chemical Structures for Index Chemicus®

Alerts by Chemical Structure are available in Index Chemicus (File 302). You can set up an Alert for a chemical structure using a MOL file or an Alert that is a combination of text and a MOL file. Although the Alert by Chemical Structure must be created in DialogLink 5, any user can receive the Alert.

Check the “Create an Alert by Chemical Structure” Quick Reference Card for more details on setting up the Alert.

Chemistry Topics of Interest

The National Academy of Sciences of the United States publishes Proceedings that include papers on some of the latest research and development in the sciences, including chemistry. In addition, each month the National Academy of Sciences ranks articles from its proceedings based on “hits” to the articles on its Web site. See what chemistry topics are getting the most attention.

Click 50 Most-Frequently-Read Articles to view abstracts and PDF versions of complete articles on biological, physical and social sciences. If you want to go directly to articles in Chemistry, click Physical Sciences for the most current articles published in the Proceedings weekly.

Call for Contributors

Participate in knowledge sharing with your colleagues interested in chemistry-related topics. Share your story suggestions with us at support.dialog.com/enewsletters/contribute/.